Microbiome Research
From bed-side to bench and back again
The microbiome plays a crucial role in health and disease and can determine the fate and efficiency of therapeutics. To understand the interaction between the microbiome and the host and the ability to modulate the microbiome will open new avenues for personalized precision medicine.
Microbiome Research
From bed-side to bench and back again
The microbiome plays a crucial role in health and disease and can determine the fate and efficiency of therapeutics. To understand the interaction between the microbiome and the host and the ability to modulate the microbiome will open new avenues for personalized precision medicine.
Technologies and Services
Within the last 20 years, a strong interaction between diseases, therapeutics and the human gut microbiome has crystallized whereby several acute and chronic diseases can cause or can be caused by disturbances of the gut microbiome, known as dysbiosis. Also drugs can cause dysbiosis or being modified by the microbiome. We enable a deeper understanding of the role of the human gut microbiome in disease conditions to identify predictive or diagnostic biomarker and therapeutic targets.
We provide a full range of microbiome research services, translating clinical problems into actionable research questions using clinical data and biosamples. Our offerings include biomarker identification, bacterial strain isolation, and a unique patient-derived microbiome modulation platform. Supported by extensive biological and technological methodologies, our customizable research lifecycle delivers results for clinical interventions. Outcomes can lead to licensable products or specialized services, with opportunities for publication and conference presentations. Partner with us for innovative microbiome research solutions.
Services in this research area are centered around the understanding of microbiome composition and function and the effects of alterations of microbiomes on the host. There is no restriction to disease areas. All our services are highly customizable and can be offered as a end-to-end study execution or ad-hoc support by conducting certain services.
Microbiome Modelling
Observing the dynamic of the microbiome in health and disease is a crucial source of information. We are experienced in microbiome-related studies, clinical and in-vitro.
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Clinical and Microbiome Data Analysis
High-throughput data sets harbor a cornucopia of information but also come with their own challenges. We can help you navigate through all stages of your project, from study design and sample size calculation, to data analysis, visualization and interpretation.
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Gut Barrier Function and Permeability
The gut barrier facilitates an intricate balancing act between supply and protection and is a crucial part of the microbiome gut-health axis. Learn about our gut permeability models and our longstanding experience with gut permeability markers in the clinical setting.
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Probiotic Strain Isolation and Characterization
Probiotic microorganisms have unique abilities to strengthen the gut barrier, inhibit pathogen growth or modulate the immune response. With our diverse panel of tests, we can highlight the strengths of your strains and help you develop a clinically relevent product.
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Innate Immunity
We speciallize in the innate immune system with a strong focus on neutrophil function and acellular immunity as potential biomarker for infection risk.
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Approaching precision medicine along the microbiome-gut-health axis.
The Team Behind Microbiome Research
Innovative research needs dedicated researchers – interdisciplinary and diverse.
